Kris Chadee Selected Research

Amebic Dysentery (Amoebic Dysentery)

1/2020	The delicate balance between Entamoeba histolytica, mucus and microbiota.
1/2018	Entamoeba histolytica Alters Ileal Paneth Cell Functions in Intact and Muc2 Mucin Deficiency.
1/2017	MUC2 Mucin and Butyrate Contribute to the Synthesis of the Antimicrobial Peptide Cathelicidin in Response to Entamoeba histolytica- and Dextran Sodium Sulfate-Induced Colitis.
1/2014	The future for vaccine development against Entamoeba histolytica.
1/2013	Entamoeba histolytica contains an occludin-like protein that can alter colonic epithelial barrier function.
11/2008	Prostaglandin E2 produced by Entamoeba histolytica binds to EP4 receptors and stimulates interleukin-8 production in human colonic cells.
10/2007	Intranasal immunization with Gal-inhibitable lectin plus an adjuvant of CpG oligodeoxynucleotides protects against Entamoeba histolytica challenge.
3/2006	Antisense inhibition of Entamoeba histolytica cysteine proteases inhibits colonic mucus degradation.

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Kris Chadee Research Topics

Disease

15	Inflammation (Inflammations) 01/2022 - 04/2007
11	Amebiasis (Amoebiasis) 01/2021 - 09/2002
10	Infections 01/2020 - 05/2010
8	Amebic Dysentery (Amoebic Dysentery) 01/2020 - 03/2006
7	Colitis 01/2021 - 11/2010
4	Inflammatory Bowel Diseases (Inflammatory Bowel Disease) 03/2013 - 11/2008
3	Amebic Liver Abscess 12/2019 - 01/2006
2	Parasitic Diseases (Parasitic Disease) 01/2022 - 12/2004
2	Giardiasis 01/2022 - 11/2017
2	Crohn Disease (Crohn's Disease) 01/2021 - 07/2011
2	Disease Susceptibility (Diathesis) 01/2021 - 01/2020
2	Stomach Ulcer (Gastric Ulcer) 01/2013 - 03/2011
2	Ulcer 03/2011 - 01/2011
1	Communicable Diseases (Infectious Diseases) 11/2021
1	Sepsis (Septicemia) 01/2020
1	Ischemia 12/2019
1	Necrosis 12/2019
1	Wounds and Injuries (Trauma) 01/2018
1	Muscle Cramp (Cramp) 01/2017
1	Disease Progression 01/2015
1	Noncommunicable Diseases 03/2013
1	Lymphocytic Colitis 01/2013
1	Neoplasms (Cancer) 01/2012
1	Diarrhea 08/2011
1	Entamoebiasis 12/2010
1	Gastrointestinal Diseases (Functional Gastrointestinal Disorders) 01/2009
1	Liver Abscess 10/2007
1	Weight Gain 05/2003

Drug/Important Bio-Agent (IBA)

13	MucinsIBA 11/2021 - 02/2003
7	CytokinesIBA 01/2022 - 01/2013
6	Cysteine Proteases (Cysteine Protease)IBA 01/2022 - 02/2003
6	VaccinesIBA 02/2009 - 09/2002
5	Proteins (Proteins, Gene)FDA Link 01/2021 - 02/2009
4	Virulence Factors (Pathogenicity Factors)IBA 01/2022 - 03/2006
4	LectinsIBA 01/2014 - 01/2004
4	Prostaglandins EIBA 04/2012 - 11/2008
3	ChemokinesIBA 01/2018 - 04/2007
3	Dextran SulfateIBA 01/2018 - 01/2017
3	sodium sulfate (sodium bisulfate)FDA LinkGeneric 01/2017 - 11/2010
3	Dextrans (Dextran)FDA Link 01/2017 - 11/2010
2	Anti-Bacterial Agents (Antibiotics)IBA 01/2021 - 11/2018
2	InflammasomesIBA 01/2020 - 10/2016
2	Interleukin-8 (Interleukin 8)IBA 01/2018 - 04/2012
2	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 01/2017 - 01/2013
2	IntegrinsIBA 05/2015 - 11/2010
2	Acetic Acid (Vinegar)FDA LinkGeneric 01/2013 - 03/2011
2	ProstaglandinsIBA 04/2012 - 11/2010
2	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 07/2011 - 01/2011
2	Pharmaceutical PreparationsIBA 02/2009 - 01/2009
2	DNA VaccinesIBA 12/2004 - 02/2003
2	Subunit VaccinesIBA 01/2004 - 09/2002
1	CalciumIBA 01/2022
1	Mitogen-Activated Protein KinasesIBA 01/2022
1	Biological ProductsIBA 01/2022
1	PAR-2 ReceptorIBA 01/2022
1	AlarminsIBA 01/2020
1	Chemotactic FactorsIBA 01/2020
1	Glycoside Hydrolases (Endoglycosidases)IBA 01/2020
1	HMGB1 Protein (HMG1)IBA 01/2020
1	IronIBA 01/2020
1	hyaluronate lyase (spreading factor)IBA 01/2020
1	CaspasesIBA 01/2020
1	SecretagoguesIBA 01/2020
1	Peroxidase (Myeloperoxidase)IBA 01/2018
1	Vascular Endothelial Growth Factor CIBA 01/2018
1	Muramidase (Lysozyme)IBA 01/2018
1	Fibroblast Growth Factors (Fibroblast Growth Factor)IBA 01/2018
1	Fibroblast Growth Factor 2 (Basic Fibroblast Growth Factor)IBA 01/2018
1	Prostaglandin-Endoperoxide Synthases (Cyclooxygenase)IBA 01/2018
1	Metalloproteases (Metalloproteinases)IBA 01/2018
1	Dinoprostone (PGE2)FDA Link 01/2018
1	R-SNARE Proteins (Vesicle-Associated Membrane Protein)IBA 10/2017
1	Chemokine CCL2 (Monocyte Chemoattractant Protein 1)IBA 01/2017
1	Antimicrobial PeptidesIBA 01/2017
1	Butyrates (Butyrate)IBA 01/2017
1	Transforming Growth Factors (Transforming Growth Factor)IBA 01/2017
1	Fibroblast Growth Factor 1 (FGF-1)IBA 01/2017
1	Intercellular Signaling Peptides and Proteins (Growth Factors)IBA 01/2017
1	CathelicidinsIBA 01/2017
1	Interleukin-18 (Interleukin 18)IBA 10/2016
1	InterleukinsIBA 10/2016
1	DefensinsIBA 03/2013
1	Glycoproteins (Glycoprotein)IBA 03/2013
1	OccludinIBA 01/2013
1	Prostaglandin Receptors (Prostaglandin Receptor)IBA 01/2013
1	Neutralizing AntibodiesIBA 01/2013
1	Ubiquitin-Protein Ligases (Ubiquitin-Protein Ligase)IBA 01/2012
1	SodiumIBA 01/2011
1	Biomarkers (Surrogate Marker)IBA 01/2011
1	Peptide Hydrolases (Proteases)FDA Link 12/2010
1	LipidsIBA 11/2010
1	dimethyloxallyl glycineIBA 07/2010
1	Interleukin-10 (Interleukin 10)IBA 02/2007
1	AcetylgalactosamineIBA 01/2006
1	Galactose (Galactopyranose)FDA LinkGeneric 01/2006
1	OligodeoxyribonucleotidesIBA 01/2006
1	Thomsen-Friedenreich antigenIBA 01/2004
1	LeptinIBA 05/2003

Therapy/Procedure

1	Biological Therapy 11/2008